On a sunny summer day in early August, the University of California at Berkeley’s Laboratory of Molecular Biology and Biotechnology (LMGB) will open its doors for the first time in almost 20 years.
The new facility will be the largest in the world, and its centerpiece will be a new, $1.6 billion laboratory and biosafety building called the Integro Health Systems (IHS).
The $1 billion facility will allow researchers to rapidly and efficiently conduct genomic and cellular research and development, with the goal of creating a new class of medicines and treatments that can be used safely and effectively for all types of cancers, heart disease, and inflammation.
Integro’s new facility is also the site of an unprecedented collaboration with the University Health Network (UHN) to support the university’s Cancer Genomics Center, the world’s largest cancer database, and the Institute for Clinical and Translational Sciences (ICTS).
“We want to use this new facility to continue to advance our knowledge, and to build on the groundbreaking work that LMGB and the UHN have done for cancer,” says Dr. Brian T. Hwang, president of Integro and former director of the laboratory.
The IHS facility will include a 10-year-old facility, a 3-year old facility, and a 3 year old facility.
It will be operated by a new consortium, led by UHU’s National Center for the Human Genome.
The LMGB/UHU consortium will collaborate on research with Integro to advance the understanding of how and why certain cancer types and diseases develop, what treatments work best for them, and how to prevent, diagnose, and treat them.
The collaboration will also be used to improve cancer therapies and develop new ways to detect, treat, and prevent cancer in other types of disease.
The goal of the project is to create a cancer-specific laboratory for genomic and cell research, and it will use a cutting-edge platform called CRISPR-Cas9 to edit and sequence the DNA of cancer cells.
This process can be replicated in the lab, where researchers can examine and analyze the DNA for cancer-associated mutations.
“The goal is to make the IHS the most advanced cancer research facility in the country,” says Michael G. Eisner, LMGB’s director.
“This is a great opportunity for the university and the world to collaborate.”
Integro has been involved in the global cancer gene research project for nearly two decades.
In 2016, the company and UH were awarded $1 million from the National Institutes of Health (NIH) to continue their work.
“It’s a big deal,” says M. Scott Fogg, a stem cell biologist at the University Hospitals Case Medical Center in Cleveland, Ohio.
“They’re bringing back the ability to do the research that was done decades ago.”
The work at LMGB has led to the creation of many cancer drugs and treatments.
A major milestone came in April 2018 when the company’s technology was used to produce the first human papillomavirus (HPV) vaccine.
In March 2019, Integro also received the prestigious BRAIN Initiative’s Genome Editing Challenge to improve the tools and tools needed to sequence and edit DNA from human genomes.
“We’re very excited to work with this group and we’re confident that we’ll be able to get a better understanding of the genes and proteins that are involved in cancer,” Fogg says.
Integra is also helping to develop technologies that can help cancer patients to improve their quality of life.
One of the company of the first projects in this effort is the Myriad Genetics Inc. (MGI) platform, which was developed by the Integra-UHX partnership.
The Myriad platform allows scientists to use genetic tools to detect and understand cancer-causing mutations in the DNA sequence of the patient’s cells.
The project is also developing a genetic test to be used in conjunction with existing medical diagnostic tests to detect genes that are associated with cancer.
“Integro has helped build the cancer-prevention and cancer-screening industry by developing the tools necessary to enable the industry to better predict and detect cancer and identify treatment options,” says Andrew W. Gopnik, MGI CEO.
“Our partnership with LMGB will help us to continue building on our previous accomplishments in building tools that can enhance the science and medicine of cancer.”
Integra’s new project is part of an ambitious new program by the university to create the most comprehensive, comprehensive, and most efficient cancer genomic resource on the planet.
The university is developing a $1-billion initiative to support this goal.
The effort will include funding for new cancer research, clinical trials, and clinical trials in patients with advanced and advanced-stage cancers; a collaboration between integros, researchers, and researchers of integro genomics, including LMGB, to develop and validate the technology to be